{"product_id":"melanotan-1","title":"Melanotan-1","description":"\u003cp\u003eMelanotan-1, also designated MT-1, afamelanotide, or [Nle4, D-Phe7]-alpha-MSH, is a synthetic linear analog of alpha-melanocyte-stimulating hormone (alpha-MSH). In laboratory research, Melanotan-1 is studied as a selective melanocortin-1 receptor (MC1R) agonist and as a tool compound for investigating the melanogenesis pathway and melanocortin-receptor signaling.\u003c\/p\u003e\n\u003cp\u003eUnlike the non-selective analog Melanotan-2, which engages multiple melanocortin receptors (MC1R through MC5R), the MT-1 research profile is weighted toward MC1R, the receptor most associated with melanin-synthesis pathways in preclinical models.\u003c\/p\u003e\n\u003cp\u003ePreclinical investigations have explored Melanotan-1 in experimental models studying:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMC1R receptor binding and selectivity\u003c\/li\u003e\n\u003cli\u003emelanogenesis and melanin-synthesis pathways\u003c\/li\u003e\n\u003cli\u003emelanocyte signaling and gene-expression models\u003c\/li\u003e\n\u003cli\u003ephotoprotection and UV-response research models\u003c\/li\u003e\n\u003cli\u003emelanocortin-receptor pharmacology and structure-activity relationships\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch4\u003eMechanistic Research Insights\u003c\/h4\u003e\n\u003cp\u003eExperimental research examines Melanotan-1 as an MC1R-selective melanocortin agonist, with downstream signaling studied primarily through the cyclic AMP (cAMP) pathway.\u003c\/p\u003e\n\u003cp\u003eAreas of investigation include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMC1R activation and cAMP signaling\u003c\/li\u003e\n\u003cli\u003etyrosinase and melanin-synthesis enzyme pathways\u003c\/li\u003e\n\u003cli\u003eeumelanin production in melanocyte models\u003c\/li\u003e\n\u003cli\u003ereceptor selectivity relative to MC3R, MC4R, and MC5R\u003c\/li\u003e\n\u003cli\u003estructure-activity relationships among alpha-MSH analogs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese mechanisms are commonly studied in melanocyte cell cultures and receptor-binding assays.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003eCompound Information\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eCompound Name:\u003c\/strong\u003e Melanotan-1 (MT-1)\u003cbr\u003e\u003cstrong\u003eAlternate Designations:\u003c\/strong\u003e Afamelanotide, [Nle4, D-Phe7]-alpha-MSH, NDP-MSH\u003cbr\u003e\u003cstrong\u003ePeptide Class:\u003c\/strong\u003e Synthetic alpha-MSH Analog (Melanocortin Agonist)\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C78H111N21O19\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~1646.9 g\/mol\u003cbr\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 75921-69-6\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003eProduct Specifications\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99%\u003cbr\u003e\u003cstrong\u003eTesting Methods:\u003c\/strong\u003e HPLC \u0026amp; Mass Spectrometry\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e Lyophilized white powder\u003cbr\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 75921-69-6\u003c\/p\u003e\n\u003cp\u003eEach batch undergoes analytical verification to confirm peptide identity, purity, and consistency.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003eStorage\u003c\/h4\u003e\n\u003cp\u003eFor optimal stability, store lyophilized peptides in a cool, dry environment away from direct light. Long-term storage conditions may vary depending on laboratory requirements.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003eResearch Use Notice\u003c\/h4\u003e\n\u003cp\u003eThis compound is supplied strictly for laboratory research purposes only. Not intended for human consumption, therapeutic use, cosmetic use, or veterinary use.\u003c\/p\u003e","brand":"Lumivive Wellness","offers":[{"title":"10MG","offer_id":52449456128280,"sku":null,"price":40.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0988\/6177\/7176\/files\/51C2701E-0F3E-42E8-BF90-76F490AB2E7F.png?v=1785200087","url":"https:\/\/shop.lumivivewellness.com\/products\/melanotan-1","provider":"Lumivive Wellness","version":"1.0","type":"link"}